Tuesday, 31 May 2016
Future of Metabolomics Dependent on Biomarker Discovery and Drug Assessment
Metabolomics is a comprehensive study of metabolites within tissues, cells, organisms, and bio fluids. A metabolite is a substance that is either part of a metabolic reaction or is produced by one. Metabolomics is utilized for data mining and for presenting the functional information of an organism’s physiological nature. It comprises the study of products and substrates of metabolism, which are affected by environmental and genetic factors. The demand for metabolomics is predicted to grow, thanks to the increasing application scope of metabolomics.
Transparency Market Research (TMR), a market intelligence company, answers a series of questions in order to provide a clearer view of the metabolomics market.
Q. What drivers and impeders will have a major impact on the market dynamics by 2024?
The increasing technological advancements in molecular biology and biochemistry have played a major role in the development of the market for metabolomics. In addition, the enhancement in analytical instruments, analysis software, and data processing have also stimulated the growth of the overall metabolomics field. Furthermore, the increasing support from governments and the increasing research funding globally for the commercialization of various products within metabolomics will also create a positive impact on the growth of the market.
Metabolomics science is also utilized extensively in drug assessment and biomarker discovery. Hence, the swift development of the biotechnology and pharmaceutical industries is supporting the development of the market for metabolomics. The increasing incidence of chronic degenerative diseases such as cardiovascular diseases and cancer, particularly in emerging nations will also augment the growth of the market in the coming years.
On the other hand, the absence of skilled professionals within metabolomics science is a major factor impeding the development of the market. In addition, the increasing data complexity and the low adoption rate of metabolomics are also amongst the prime factors that may pose a negative impact on the growth of the market.
Q. How is the increasing usage of metabolomics in life sciences a key opportunity in the market?
Owing to the increasing application areas of metabolomics such as phenotyping of genetically modified plants, determination of gene function, and monitoring responses to abiotic and biotic factors, metabolomics is sought after globally. Metabolomics is utilized for bridging the gap between genotype and phenotype by providing a complete view of the cell functioning. It also helps in the identification of novel alterations within certain metabolites.
Metabolomics has gained significance as a tool within life sciences owing to it being a relatively precise and faster technique that can be implemented with either a specific focus or in a general manner for gaining new knowledge about biological systems.
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Q. What is impeding the adoption of metabolomic technologies in big pharma companies? What is the predicted future of this discipline?
A number of big pharma companies are still negligent in adopting metabolomic technologies in comparison with genomic and proteomic research. This is due to the lingering uncertainties of the advantages presented by metabolomics owing to the failed genomics and proteomics research programs. However, some recent advancements have successfully dispelled some of these doubts. The key focus of metabolomics is on 20 to 100 different metabolites. Although, this comprises a very small part in comparison to other field of ‘omics,’ this discipline is still excelling in the discovery of biomarkers. For instance, as per a recent publication by the American Association for Cancer Research on Cancer Epidemiology, Biomarkers & Prevention, metabolite profiling is being extensively utilized in the study of prostate cancer in order to identify diagnostic, prognostic, and predictive biomarkers. Hence, such growth opportunities will boost the overall growth of the market in forthcoming years.