Friday 16 June 2017

Global Photorejuvenation Equipment Market Trends & Industry Forecast by 2016 - 2023

The photorejuvenation equipment market can be segmented by technology, application and geography. Based on technology these equipment can be further sub-segmented into three broad categories namely mechanical (LED and laser), chemical (chemical peels) and thermal. Based on the application this therapy is used in treatment of acne, Rosacea, freckles and others. Geographically, North America and Europe regions exhibit large consumption of these services owing to continuously increasing population of working women and increasing preference for these treatments among elderly woman population. Safety concerns and technology skills govern the market growth.


Photorejuvenation, one of the forms of facial rejuvenation, employs intense broad wavelength light which is absorbed by brown and red pigment beneath the skin. This process distributes energy to both epidermis and deep layers of the skin but results in some damage to the epidermis and this is minimized by applying chilled crystals. Reduction of appearance of brown spots, redness and excess blood vessels (sun damage) constitutes the primary function of Photorejuvenation treatments. In addition, it may provide a smooth and soft texture to the skin and may reduce the fine lines or wrinkles on the face. These treatments are performed on chest, neck, face, shoulders and hands. In general these treatments are performed on the areas that exhibit the signs of photo-aging.

Furthermore, Photorejuvenation therapy improves the symptoms of Rosacea and can have significant impact on the quality of life of the patients.  Other treatment areas include angioma, red or blue leg veins, cherry, lentigines and matted telangiectasia, tattoo removal and birthmark removal. Various light emitting diodes (LEDs), intense pulsed light and lasers constitute photorejuvenation equipment. Photorejuvenation is performed for somewhere around 15 minutes to 45 minutes and during this process intense pulsed light is delivered to the skin through explicit filters and is passed in several settings (series of six treatments every three to four weeks) to ensure optimum results.

The absorption of light energy stimulates the production of collagen and this inturn softens the skin thereby resulting in reduction of fine lines and wrinkles. This process has been considered safe worldwide as it affects only the targeted tissues and retains the intactness of the surrounding tissues. The limitations of this process include the appearance of short term redness, darkening of age spots and bruising. Sometimes this process can be combined with facelift to render complete facial makeover.

Photorejuvenation equipment market is still in the nascent stages in Asia Pacific and Rest of the World regions, but these exhibit lucrative growth opportunities due to increasing demand for these therapies over expensive cosmetic surgeries and increasing awareness along with high disposable incomes.

Some of the major factors driving the market growth include minimally invasive nature of these procedures followed by low cost of the procedures in comparison with other surgeries. In addition, low turnaround time coupled with few side effects will further fuel the market growth. On the other hand factors such as increased risk of developing skin cancer, and adverse hypersensitivity reactions might limit the acceptance and growth of photorejuvenation equipment. Abbott Medical Optics, Biolitec AG, Lumenis Ltd., Candela Corporation, Erchonia Medical, LISA Laser Products, Alcon, Inc., Dornier Medtech GmbH, AESCULIGHT LLC, Deka Laser, Nidek Company Ltd., and Vascular Soultion, Inc. are some of the companies engaged in developing photorejuvenation equipment.

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MicroRNA Tools Market - Global Industry Analysis and Forecast 2016 - 2023

The miRNA research, driven by its therapeutic and diagnostic potential has fueled the growth of global miRNA tools market. The recent developments in the molecular biology and genomic technologies will uplift the market. Moreover higher research funding, increased outsourcing to contract research in developed countries and increased investments by the foreign countries in the developing nation such as China, India etc. will create an opportunity and drive the miRNA tools market. High cost involved in the manufacturing of research tools and the lack of experienced professionals will be responsible to restrain the growth of the market.


MicroRNA, referred as miRNA is a class of naturally occurring, small non-coding RNA molecule, which is found in plants, some of the viruses and animals. Over the past decade, it has become gradually clearer that it plays an important role in the regulation of gene. Within 10 years of research has evolved from discovering the presence of miRNA in mammals to their therapeutic applications in several diseases. Inherent to the fast developments and overall excitement surrounding miRNA findings is the rising need for applicable and validated experimental tools to allow the researchers to elucidate the expression and biological function of miRNA. It presents a fast growing research area with vast probability to discover the novel and exciting mechanism related to physiology and pathology. Technological developments such as bioinformatics and next generation sequencing (NGS) permitted the identification of excessive number of additional putative miRNA in different organisms in current years.

The vital first step in miRNA research is detection of miRNA, governed by many regulatory checkpoints. Though it is hard to estimate the whole number of miRNA, to date, over 2000 human, miRNA are recognized and deposited in miRBase. The process of identifying miRNA is still challenging and complex and needs an interdisciplinary strategies and it should have integrational experimental approached with computational methods. Scientist can now use the advanced tools to resolve the complex findings of miRNA research.

The miRNA tools market is segmented into tools, end users and geography. The tools classified as microarrays, next generation sequencing (NGS), quantitative real time PCR (qRT-PCR), northern blotting, in situ hybridization (ISH). The Quantitative real time PCR (qRT-PCR) is known to be the largest and fastest growing segment in this market. The end users covered are biotech companies, academic and research institutes. Based on the geography, miRNA market segmentation is North America, Europe Asia Pacific, Latin America, and Middle East and Africa. United States reported to have the largest share in miRNA market followed by Europe. Due to the increased investment by foreign countries in China and India expected to be the fastest growing countries in the miRNA research tools market

Some of the major players in the microRNA research tools market are Affymetrix, Agilent Technologies, Exiqon A/S, Illuminia, Life Technologies Corporation, Phalanx Biotech Group, Qiagen NV, Roche Holding AG and Thermo Fisher Scientific Inc.

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Global Sexually Transmitted Disease Testing Market by Type & Application 2016 - 2024

Sexually transmitted diseases, also referred to as venereal diseases, are infections transmitted through sexual contact and are caused by viruses, bacteria, and parasites. These infections usually do not show any symptoms. Medically, when symptoms are diagnosed through various tests, a patient is said to be suffering from sexually transmitted disease or STD. Apart from sexual contact, STDs can in some cases also be transmitted through childbirth, breastfeeding, and shared usage of needles. Gonorrhea, HIV, HPV, chlamydia, and syphilis are the common types of STDs. According to data released by the U.S. Centers for Disease Control and Prevention in 2014, there has been an increase in the reported cases of STDs across the U.S. for the first time since 2006.

Rise in incidences of unprotected sex has led to an increase in the prevalence of sexually transmitted diseases, thereby propelling the demand from the global sexually transmitted disease testing market. STD testing is usually advised by physicians even if a person does not show symptoms but has had unprotected sex. There are various types of STD diagnostics available in the market such as viral load monitoring, genotyping, immunoassays, and molecular diagnostic.          
                                                             
Global Sexually Transmitted Disease Testing Market: Overview   

Lack of awareness about sexually transmitted diseases and the rising incidences of unprotected sex have majorly contributed to the growing prevalence of sexually transmitted diseases. The global sexually transmitted disease testing market has been boosted by the high number of patients suffering from STDs, especially in the age group of 15 years to 24 years. In fact, this age group is the most vulnerable to STDs even though it is relatively a small portion of the sexually active population.

Recommendations from various regulatory authorities for annual STD screening for sexually active men and women are expected to further fuel the demand for STD testing. STD screening services are now widely covered under health care services and are likely to augment the growth of the global STD testing market. For example, plans under the U.S. Affordable Care Act offer coverage for recommended STD screening services without cost-sharing. Regulatory authorities such as the World Health Organization have outlined strategies for the prevention and control of STDs. Research activities are being carried out to understand the growing prevalence of STDs, particularly Syphilis, among gay and bisexual men. All of these factors are anticipated to drive the growth of the global sexually transmitted diseases testing market.

Global Sexually Transmitted Disease Testing Market: Region-wise Outlook  

The global sexually transmitted disease testing market has been segmented into four key regions: Asia Pacific, North America, Europe, and Rest of the World. In North America, a reported rise in the number of people affected with STDs such as gonorrhea, chlamydia, and syphilis has fuelled the demand for sexually transmitted disease testing. Favorable government policies are also expected to boost the demand from the regional market. Recently, the outbreak of Zika virus and the possibility of the transmission of Zika virus through sexual contact have led authorities in countries in Africa and South America to recommend Zika virus testing.

Prominent players in the global sexually transmitted disease testing market include Bayer AG, Merck and Company Inc., Abbott Laboratories, and Home Access Health Inc.  

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X-ray Crystallography Market - Global Industry Volume and Region Analysis - 2023

X-ray crystallography is primarily utilized for determining arrangement of particles inside crystals. The diffraction of x-rays, after they are projected on a crystal, are measured by the crystallographer to determine the electron density of the crystal and also provides a three-dimensional image of the same. X-ray crystallography has been instrumental in determining types and lengths of chemical bonds and size of atoms among others. This is achieved primarily because crystal forms are available for semiconductors, metals, minerals, proteins and salts among others. An X-ray crystallography functions by projecting x-rays on a crystal held between the x-ray source and a screen. The diffracted rays are captured on the screen as dotted patterns. Fourier transformation mathematics is then applied for obtaining the shape of the crystal from the pattern obtained on the screen. X-ray crystallography is very important for synthesis of new drugs and medicines as it aids in determining the structure of their precursors.


Some of the major factors fuelling the demand for the global X-ray crystallography market is the increasing research and development being conducted for better drugs and medicines by the pharmaceutical industry. Factors such as development of multi-drug resistant bacteria, constantly evolving pathogenic viruses and quest for developing drugs for various types of cancer among others have been fuelling the demand for newer medicines. Such increase in demand for medicines has in turn fuelled the demand for x-ray crystallography since it aids in developing structure-based drug design for targeting specific bio-molecules among others. Additionally, x-ray crystallography is also been used for obtaining quantitative results of samples across industry verticals such as cement and wood among others. Such varied applications have also been positively impacting the growth of x-ray crystallography market. However, requirements for developing crystals, of the product to be studied, prior to utilizing x-ray crystallography have been a significant restraining factor. Also development of newer technologies such as x-ray free electron lasers can pose a threat for the x-ray crystallography market. The increasing research and development for advanced targeted drug delivery systems poses good opportunity for the global x-ray crystallography market.

By product type, the global x-ray crystallography market can be segmented into instruments, reagents and services.  Instruments segment is expected to remain the dominant segment during the forecast period. By applications, the x-ray crystallography market can be further segmented in to academic research, industrial, mineralogy & metallurgy, chemicals, pharmaceuticals and others. Pharmaceuticals segment is expected to remain the largest segment in 2023. By geography, the global x-ray crystallography market can be segmented into North America, Europe, Asia-Pacific (APAC) and rest of the world (RoW). North America can be expected to remain the leader in x-ray crystallography market globally, during the forecast period.

Some of the key companies leading the x-ray crystallography market globally are Thermo Fisher Scientific, Inc. (U.S.), Rigaku Corporation (Japan), Bruker Corporation (U.S.), Anton Paar GmbH (Austria), Danaher Corporation (U.S.), MiTeGen, LLC (U.S.), PerkinElmer, Inc. (U.S.), PANalytical B.V. [Spectris] (The Netherlands), Molecular Dimensions (U.K.), and Olympus Corporation (Japan) among others.

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Nanocapsules Market - Global Industry Volume and Region Analysis - 2024

Nanoparticles are solid colloidal particles that include both nanospheres and nanocapsules. Nanocapsule is any nanoparticles that consist of a shell and a space in which desired substances may be placed. It is made up of a nontoxic polymer. They are also known to be drug delivery agents in the size range of 10-1000 nm. These capsules are made up of molecules called as phospholipids such as liposomes. Now-a-days many other materials such as variety of polymers have been used to make nanocapsules by self assembly process. Polymeric capsules are studied extensively as particulate carriers in the medical and pharmaceutical fields as they act as good drug delivery systems as a result of their sustained and control release property and subcellular size. 

Nanopharmacology is a new branch of pharmacology which deals with the application of nanotechnology in the field of nanomedicine. This is a potential step towards curing and prevention of disease by using molecular knowledge about human body and molecular tools. Nanopharmacology studies the interaction between nanoscale drugs and proteins such as DNA, RNA and cells & tissues. It also studies the interaction between physiological systems and traditional drugs at nanoscale level. 


The ultrafine size of nanocapsules itself is one of the useful function as the finer drug are suitable to be absorbed easily through biological systems. The special features and functions of nanoparticles include slow release: the capsules releases drugs molecules slower over a long period of time, quick release: the capsule shell breaks and comes in contact with a surface, specific release: the shell is designed to break open when a molecule receptor binds to a specific chemical and moisture release: the shell breaks down and releases drug in the presence of water among other features. The state of the art nanocapsulation medications include drugs deliver to specific locations within the body, cuts down on the amount of drug per dose and reduces the risk of side effects. The only limitation is that it is designed to target pre-determined areas.

Cancer, neutraceuticals, ethyl alcohol absorption, food usage and self healing materials are the major applications of nanocapsules. Water soluble polymer shells are manufactured to deliver a protein known as apoptin into cancer cells. Neutraceuticals are substances which are placed into food to enhance nutrition. The smaller the nanocarrier, the better the delivery particles and solubility of neutraceuticals. Nanocapsulation in foods includes the changing of texture, coloring, flavoring and stability in shelf life. Nanocapsules are known to reduce damage that is caused by high loads for components in microelectronics, polymeric coatings and adhesives.

Growing pharmaceutical industry along with the rising demand for nanocapsules are expected to be the major factor driving the global nanocapsules industry. The growing demand from the end user industry is also expected to boost demand for nanocapsules in the near future.

Asia Pacific is expected to be the largest consumer of nanocapsules due to growing pharmaceutical industries in the region. North America and Europe are also expected to boost demand for nanocapsules owing to the growing demand from the end-user industries for various applications.

Some of the major players profiled for global nanocapsules market include: Capsulation, Sanzyme Ltd, PlasmaChem GmbH, NoCamels, Indian Instruments Manufacturing Company, Encap, Sintef, and Carlina Technologies among others.

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Global Erythropoietin Stimulating Agent Market Key Trends & Industry Forecast 2015 - 2023

GlobalErythropoietin stimulating agent market are driven by increasing number of patients suffering from anemia, anemia induced due to cancer, end stage renal disease (ESRD) and HIV treatment. In June 1989,Epoetin alfa was the first drug for EPO, manufactured by Amgen Inc. U.S FDA approved itunder the trade name “Epogen”.The global market for erythropoietin drugs are expected to grow in near future as increased cases of cancer and renal problem haveregistered. With the expiration of Amgen’s patent for Epogen, it has helped the production of other biosimilars EPO drugs. Hence, availability of many biosimilar drugs has renderedlow-cost option to the patients, therefore particularly, in the developing regions the adoption of EPO drugs have increased.


Blood carries oxygen which is required for a healthy body functioning. When the concentration of oxygen is reduced in the blood then an oxygen-sensing protein present in the kidney identifies the deficiency of oxygen gradient in the blood and then induces the EPO production,which then turns upon the erythroid cell line in the bone marrow to stimulate hematopoiesis and thus it response to the change in blood oxygen gradient. Endogenous erythropoietin (EPO) is a glycoprotein hematopoietic hormone, which is synthesized, in the renal tubules. EPO helps in controlling and regulating the mechanism of erythropoiesisin the bone marrow. Due to anemia and renal problem, the production of erythropoietin (EPO) istroubled, resulting into fatigue, weakness, shortness of breath, pale skin and insomnia.For treating anemia,chemotherapy induced anemia, renal disorders and others erythropoietin stimulating drugs (EPO) are used.For development of synthetic form of erythropoietin drugs such as epoetin alfa, epoetin beta, darbepoetin alfa, epoetin delta, epoetin omega and others with the help of improved recombinant DNA technology.Recombinant erythropoietin is an artificialformof natural erythropoietin. These are made by cloning the gene for erythropoietin. Among synthetic EPO’sepoetin alfa, epoetin beta, epoetin omega, epoetin delta and darbepoetin-alpha are used extensively. Epoetin delta is another recombinant EPO that is been used for treating patients with chronic kidney disease (CKD).

Based on product type erythropoietin stimulating agent can divided as Epoetin-alfa, Epoetin-beta, epoetin omega, epoetin delta and darbepoetin-alpha. Application of erythropoietin stimulating agents are classified as anemia, cancer chemotherapy, kidney disorders (ESRD and dialysis), antiretroviral treatment (ART) and others (neural disease and wound healing), 

Some of the major players in erythropoietin stimulating agent market are Amgen Inc., Biocon, Celltrion, Inc., Hospira Inc., Intas Pharmaceuticals, Johnson & Johnson, Ranbaxy Laboratories Ltd., Roche, LG Life Sciences Ltd. and Teva Pharmaceutical Industries Ltd.

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Preventive Healthcare Technologies and Services Market will expand at a 9.70% CAGR from 2020

The competitive landscape of the global preventive healthcare technologies and services market includes players such as Dilon Technologies Inc., Alere Inc., Medtronic Inc., Healthways Inc., Omron Healthcare Inc., Merck & Co. Inc., and ScriptPro LLC. The key players are investing heavily in proteomics and genomics with the increased demand for personalized medicines. Furthermore, the market players are focusing on emerging economies where the market has a significant potential to grow in the near future. 

The global preventive healthcare technologies and services market is anticipated to expand at a CAGR of 9.7% during the period from 2014 to 2020. The overall market was worth US$72.8 bn in 2013 and is projected to reach a valuation of US$144.8 bn by 2020.


High Cost of Installation to Restrain Growth of Global Preventive Healthcare Technologies and Services Market

Increasing public awareness about prophylaxis and constructive government policies have played a pivotal role in the growth of the global preventive healthcare technologies and services market. The introduction of advanced technologies has significantly reduced the cost of healthcare. However, high costs of installation and maintenance of healthcare IT solutions have dampened the adoption of preventive healthcare technologies and services. “Deficient patient engagement activities have hampered the motivation of physicians and pharmacists to adopt preventive healthcare technologies,” a TMR analyst notes.

Favorable Regulatory Environment Augments Demand for Preventive Healthcare Technologies and Services across North America

North America remains the largest market for preventive healthcare technologies and services and is anticipated to retain its position during the forecast horizon. A conductive regulatory environment and a comprehensive healthcare reimbursement scenario have helped the growth of the market across this region. In 2003, the United States Medicare Prescription Drug Improvement and Modernization Act made provisions for physicians to avail grants worth US$50 mn to cover the costs of acquisition, installation, and upgrade of preventive healthcare software solutions and technologies. The act also made provisions for availing funds for training staffs. This significantly encouraged the regional healthcare facilities to adopt IT services, thereby aiding the growth of the global healthcare technologies and services market.

Lack of Robust Healthcare Structure Hampers Growth of Global Preventive Healthcare Technologies and Services Market across Asia Pacific

Europe is the second largest market for preventive healthcare technologies and services. Though the market has ample opportunities to grow across Asia Pacific and Rest of the World, the rate of adoption of preventive healthcare services in these regions is expected to be slow. “The sluggishness in the growth of these regional markets can be attributed to the lack of a robust healthcare infrastructure,” TMR report states.

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