Government Support Crucial for Widespread Adoption of Stem Cell Therapy

Stem cells are a type of human cells that give rise to the various types of cells found in the human body. Stem cells hold the potential to evolve into various types of human tissue, which has led to a growing acknowledgement of the obvious medical potential of this property. Stem cell therapy is becoming increasingly common in the treatment of various diseases and the increasing research in the field is expected to further drive the medical applications of stem cells in the coming years.

According to Transparency Market Research, government support is expected to be crucial in the global stem cells market’s expected rise from a 2013 valuation of US$26.3 bn to a valuation of US$119.5 bn by 2018. The market is expected to exhibit a robust 24.2% CAGR between 2012 and 2018.

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What are the major advances in the field of stem cells and their medical application?

In July 2016, a joint Dutch-Canadian research effort succeeded in discovering a viable method of increasing the amount of stem cells obtained from cord blood. Cord blood, which is blood from the placenta, contains a relatively small amount of stem cells per unit. The method formulated in the research allows researchers to increase the amount of stem cells obtained from cord blood, making this is a crucial advancement in the field of stem cell therapy. 

The team discovered that mirR-125a, a microRNA, is responsible for the property of stem cells to self-renew. This genetic ‘switch’ remains activated in stem cells but is inactivated in the progenitor cells formed from the division of stem cells. Success in activating this switch would result in self-sustaining production of stem cells, which will be a major boost for the global stem cell therapy market.

In April this year, a research team at McMaster University in Hamilton, Ontario, discovered the protein responsible for the growth and development of blood stem cells. The Musashi-2 protein could be the key to helping thousands of patients of various blood disorders, as understanding the ambit of the protein could allow researchers to increase the number of viable stem cells available for therapeutic use.

What are some of the major drivers for the stem cells market?

The key driver for the global stem cells market is the increasing government support across the world. As widespread incorporation of stem cell therapy allows a nation to significantly improve the overall healthcare scenario, countries in North America and Western Europe have provided solid support to stem cell research. The acceptance of stem cell therapy in emerging regions is still lagging behind due to the lack of advanced medical infrastructure to adopt stem cell therapy, but the steady improvement of the healthcare sector in countries such as India and China is likely to be a major growth driver for the global stem cells market.

The increasing prevalence of neurodegenerative disorders is another major driver for the global demand for stem cells. Neural tissue can’t be regenerated or replaced as easily as structural tissues, and the ability of stem cells to develop into human cells provides the perfect avenue for treatment of neurodegenerative conditions.

Increasing Screening Activities Provides a New Perspective to Global Stem Cells Market

Therapy that uses stem cells – undifferentiated human cells – to treat a range of diseases is called stem cell therapy. In recent years, the global stem cells market has grown due to several reasons. The biggest advantage of stem cells is their ability to differentiate into specialized cells of the human body.

Increasing Research Activities Motivate Global Stem Cells Market

A report published by Transparency Market Research states that the global stem cells market was valued at US$26.2 bn in 2013 and is expected to reach $119.5 bn by 2018. This growth, at a CAGR of 24.2% from 2012 to 2018, is completely attributable to the growing support from various governments in the world for clinical research and development of stem cell therapy. In addition to this, the expansion of the medical tourism industry, growing number of stem cell banking services, and high number of unmet medical needs are driving the global stem cells market. Some of the other factors improving the prospects of the global stem cells market are the increasing availability of therapeutic research activities and stem cell banking services, and rising awareness about drug discovery and screening and regenerative treatment options.

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BrainStorm Cell Therapeutics’ NurOwn Could be a Cure for ALS

Some of the important players engaged in the global stem cells market are Cellartis AB, Stemcelltechnologies Inc., Biotime Inc., Cellular Engineering Technologies, Cytori Therapeutics Inc., Bioheart, Celgene Corporation Inc., Osiris Therapeutics, California Stem Cells Inc., Angel Biotechnology, Brainstorm Cell Therapeutics, and Advanced Cell Technology Inc. Several players in the market are trying to solve chronic conditions and diseases with stem cell therapy. For instance, Brainstorm Cell Therapeutics announced that the Data and Safety Monitoring Board (DSMB) conducted the second round of its pre-planned safety review for the double-blind, randomized, placebo-controlled phase 2 clinical trial of NurOwn® for usage in the treatment of amyotrophic lateral sclerosis (ALS). 

DSMB stated that Brainstorm could continue its study, as no safety concerns were found in the trial. Data collected for 47 out of 48 patients showed no adverse issues, lab abnormalities, or protocol deviations related to the trial. BrainStorm Cell Therapeutics’ NurOwn uses a technique developed by Profs. Eldad Melamed and Daniel Offen, Tel Aviv University. It relates to growing and improving stem cells taken from the patients’ own bone marrow. As these cells secrete high levels of nerve-growth factors, they protect motor neurons present in the body, thereby promoting motor neuron growth and restoring nerve-muscle interaction. Such efforts are expected to change the life expectancy of ALS patients and the whole disease management scenario for ALS in the near future. 

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Currently, North America dominates the global stem cells market. Europe holds the second position with a market share of over 25% in the overall stem cell market. Though analysts predict that this market will reach newer heights in the coming years, the strict regulatory framework against the unethical harvesting of stem cells and high prices of stem cell treatments will limit the growth of this market.