Increasing Incidence of Cancer Boosts Opportunities for Companies in Molecular Cytogenetics Industry

Molecular cytogenetics is used as a tool for the examination of chromosomal anomalies and research relating to these anomalies. This technique is chosen over the generic chromosomal banding methods as the old techniques deliver low resolution results and at times escape the detection of various variations. Breakthrough technologies such as aCGH and FISH are expected to provide new dimensions to the research and development projects in the field of molecular cytogenetics. 

According to a report published by Transparency Market Research, the global market for molecular cytogentics is projected to exhibit a CAGR of 23.40% from 2013 to 2019. The market stood at US$0.4 bn in 2012 and is likely to reach US$1.9 bn by 2019. 

How technological advancements fuel demand for molecular cytogentics?

As molecular cytogenetics is more dependable than the other traditional techniques used for the diagnosis of chromosomal abnormalities, the technological advancements in this segment are expected to spur the adoption of this technique in future. Breakthrough technologies such as aCGH and FISH are being considered as priceless tools for the analysis of complex diseases, gene discovery, and gene mapping. These techniques also facilitate the diagnosis of solid molecular tumors and hematological malignancies along with their prognosis. These techniques are also known for their speed, sensitivity, accuracy, and high resolution, which encourage healthcare providers to adopt them. The growing importance of molecular cytogentetics in laboratories has led to further advancements in the technique such as digital imaging and improvement in fluorescence microscopes. The implementation of these techniques in laboratories and diagnostic centers is expected to boost theor emand further in future.  

What factors are expected to drive the adoption of molecular cytogenetics across diagnostic centers and laboratories?

The introduction of advanced technologies in molecular cytogenetics diagnosis is expected to encourage more investments in the research and development projects by non-government and government institutions. As technological advancements increase, more institutions are adopting molecular cytogenetics to get appropriate and cost effective results regarding chromosomal anomalies. 

The rising incidences of cancer globally have also led to the adoption of molecular cytogenetics for its diagnosis. The growing awareness about chromosomal abnormalities among people and their inclination towards personalized medicines are also projected to drive the demand for molecular cytogenetics diagnosis. 

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However, the easy accessibility of medical reimbursement policies and lack of transparency may hinder the growth of the molecular cytogenetics market in future. 

North America held the largest share in the global molecular cytogenetics market followed by Europe in 2012. The growing number of research laboratories in these regions is the major factor fuelling demand for molecular cytogenetics. Asia Pacific is projected to emerge as the fastest developing market for molecular cytogenetics due to rising population in the region. The leading companies in the market are entering into collaborations to carry out more researches in the segment. The key players operating in the molecular cytogenetics market are Abbott Laboratories, Oxford Gene Technology, Agilent Technologies, Bio-Rad Laboratories, and Illumina Inc.

Molecular Cytogenetics Market is Expected to Reach USD 1.97 Billion Globally in 2019: Transparency Market Research

According to a new market report published by Transparency Market Research “Molecular Cytogenetics Market (Technologies: FISH and aCGH; Applications: Genetic Disorders, Cancer and Personalized Medicine) – Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2013 – 2019,” the global molecular cytogenetics market was valued at USD 469.2 million in 2012 and is estimated to reach a market worth USD 1.97 billion in 2019 at a CAGR of 23.4% from 2013 to 2019.

Browse the full report at http://www.transparencymarketresearch.com/molecular-diagnostics-market.html

Molecular cytogenetics is emerging as an indispensable tool in the field of research and diagnosis. Until the advent of molecular cytogenetics techniques in 1980s, chromosomal analysis was mainly based on banding patterns. Although, the traditional banding techniques encountered problems such as low resolution and poor quality analysis. However, breakthrough in fluorescence in situ hybridization (FISH) and array-comparative genomic hybridization (aCGH) techniques has enhanced the diagnosis of chromosomal anomalies particularly in tumor and hematological malignancies. Nowadays, cytogenetics techniques are being considered mandatory in diagnosis and prognosis of leukemia. The techniques are considered as a standard laboratory test since they provide global screening of abnormalities. The scope of molecular cytogenetics is increasing with the rising cancer incidences worldwide and growing popularity of personalized medicines. 

The ability of FISH technique to study cells at an interphase stage of the cell cycle has made the technique a breakthrough in molecular cytogenetics field. FISH technique is used in the research of diverse applications such as cancer, cardiovascular and genetic disorder. The impetus of FISH technique is a direct result of improved understanding of sequence, structure and function of human genome. Similarly, supported by technological advancements in fluorescent microscopes and digital imaging, FISH technique has emerged as a preferred tool in molecular cytogenetics. The technique facilitates the analysis of sub-chromosomal regions and the identifications of small translocations thereby, routinely used in clinical applications. Owing to the techniques’ sensitivity and specificity, FISH is significantly used in number of cytogenetic and pathological laboratories.

The advent of aCGH is ushering new standards for the analysis of genome. The technology has turned out to be a greatest driver for the molecular cytogenetics market as it is overcoming the resolution problems associated with traditional banding techniques. aCGH is poised to witness a significant growth in the market and is likely to emerge as the fastest growing technology segment. aCGH has propelled the cytogenetics market from the microscopes to computers and thus, facilitated simultaneous analysis of thousands of discrete regions of the genome. 

Similarly, the technique is gaining popularity as one assay performed on this technique is comparable to thousands of FISH experiments and hence, saves time and cost. Moreover, the technique is expected to rapidly supplant FISH technique owing to further technological advancements in the technique. Likewise, increasing sensitivity of the aCGH technique is preferred as a primary diagnosis tool followed by validation with FISH. The technique is emerging as a powerful tool for high resolution analysis of sub-microscopic chromosomal abnormalities. aCGH is also evolving as a method of choice for molecular cytogenetics by the researchers owing to its work flow advantages and cost effectiveness. 

North America accounts for the largest share of the molecular cytogenetics market followed by the European region. The markets for these regions are driven by factors such as increased level of public awareness, rising cancer incidences and large number of research institutes engaged in cytogenetics field. However, Asia-Pacific region is likely to emerge as the fastest growing region over the analysis period. Cancer diagnosis is likely to witness a significant growth and emerge as the fastest growing segment during analysis period with a CAGR of more than 20%.  

The growing demand for molecular cytogenetics techniques in research and data interpretation has resulted in quick expansion of manufacturers’ product portfolio. The manufacturers are focused on building aggressive strategies for the development of innovative products that would cater research and diagnostic sectors. The vendors are eager to tap the emerging regions and end-users of this market. Major players engaged in development of innovative molecular cytogenetics techniques are Abbott laboratories, Affymetrix, Inc., Applies Spectral Imaging, BI Biological Industries, Life Technologies Corporation, Roche Diagnostics, Oxford Gene Technology, Illumina, Inc., among others.   

The molecular cytogenetics market is segmented as follows:
• Molecular Cytogenetics Market, by Technology
o FISH
o aCGH
• Molecular Cytogenetics Market, by Application
o Genetic Disorders
o Cancer
o Personalized Medicine
o Others
• Molecular Cytogenetics Market, by Geography
o North America
o Europe
o Asia-Pacific
o RoW
 
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